Simple Green Purification of Spilanthol from Natural Deep Eutectic Solvent and Ethanolic Acmella oleracea (L.) R.K. Jansen Extracts Using Solid-Phase Extraction
Spilanthol is a major N-alkylamide constituent of Acmella oleracea (L.) R.K.Jansen with diverse pharmacological properties.We recently showed the applicability of NADES (natural deep eutectic solvents) for the green extraction of spilanthol.However, the purification of targets from NADES poses a challenging step due to their non-volatility.A simple